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Chem Help ASAP
United States
Приєднався 15 бер 2019
Master AP, IB, and college chemistry in the subject areas of general, organic, analytical, and medicinal. With over 30 years of teaching and tutoring experience, we frequently post videos to help students and support teachers.
We have a website (www.chemhelpasap.com) and are active on Twitter (@ChemHelpASAP) and Facebook ( Chem-Help-ASAP-106211130874519/). See direct links below.
end of 1st year - 215 subscribers, 463 hours, 16,200 views
end of 2nd year - 1,430 subscribers, 5,100 hours, 132,000 views
end of 3rd year - 3,510 subscribers, 14,200 hours, 377,000 views
end of 4th year - 6,570 subscribers, 26,500 hours, 713,000 views
end of 5th year - 10,560 subscribers, 43,000 hours, 1,200,000 views
We have a website (www.chemhelpasap.com) and are active on Twitter (@ChemHelpASAP) and Facebook ( Chem-Help-ASAP-106211130874519/). See direct links below.
end of 1st year - 215 subscribers, 463 hours, 16,200 views
end of 2nd year - 1,430 subscribers, 5,100 hours, 132,000 views
end of 3rd year - 3,510 subscribers, 14,200 hours, 377,000 views
end of 4th year - 6,570 subscribers, 26,500 hours, 713,000 views
end of 5th year - 10,560 subscribers, 43,000 hours, 1,200,000 views
Applications of Electrolytic Cells
In this video we discuss electroplating with electrolytic cells. We work through several examples to determine the amount of metal that will plate, but also what current is needed to plate out a certain amount of metal. We also discuss the order in which a mixture of metals will plate out of solution.
Переглядів: 81
Відео
Applications of Galvanic Cells
Переглядів 483 місяці тому
In this video we work through problems where we use E cell to calculate Gibbs free energy and also the equilibrium constant. We also draw some general conclusions about the sign of free energy, the sign of E cell and the magnitude of Keq.
Electrolytic Cells
Переглядів 223 місяці тому
In this video we discuss how electrolytic cells are different from galvanic cells and work through several examples.
Galvanic Cells
Переглядів 213 місяці тому
In this video we discuss galvanic cells. We will calculate E cell for several examples.
Gibbs Free Energy
Переглядів 693 місяці тому
In this video we calculate Gibb's Free Energy for a reaction. We also discuss how Gibb's Free Energy can be used to determine if a reaction is thermodynamically favorable or not as well as how Gibb's Free Energy relates to entropy and enthalpy. We finish by using Keq to calculate Gibb's Free Energy and drawing general conclusions about the magnitude of Keq and the sign of Gibb's Free Energy.
Entropy
Переглядів 1053 місяці тому
In this video we cover what entropy is and what processes increase and decrease entropy. We also calculate entropy for a chemical reaction.
Titration of a Weak Acid with a Strong Base
Переглядів 533 місяці тому
In this video we work through a titration problem with a weak acid and a strong base. We first calculate how many milliliters of base is needed to reach the equivalence point, then we start with the pH of the weak acid. We calculate the pH of the solution 5 milliliters before the equivalence point, the pH at the equivalence point, and the pH 5 milliliters after the equivalence point. Lastly, we...
Titration of a Strong Acid with a Strong Base
Переглядів 373 місяці тому
In this video we titration a sample of a strong acid (nitric acid) with a strong base (sodium hydroxide). We calculate our start pH, how many milliliters we need to add to reach the equivalence point, what the pH is 5 milliliters before the equivalence point, the pH at the equivalence point and 5 milliliters after the equivalence point. We also look at the titration curve and point out the most...
Acid Base Indicators
Переглядів 673 місяці тому
In this video we discuss what an indicator is and how you would choose an indicator for a titration.
How Buffers Work and Buffer Capacity
Переглядів 613 місяці тому
In this video we first discuss the action of a buffer. How does it maintain the pH when you add either a strong base or a strong acid? Next, we work through several calculations to determine buffer capacity. We will calculate the pH of a buffer when a small amount of strong base is added and then calculate the pH when a large amount of strong base is added. This gives insight into the optimal r...
Calculating pH of Polyprotic Acids
Переглядів 2133 місяці тому
In this video we calculate the pH of sulfuric acid, a diprotic acid, and phosphoric acid, a triprotic acid. Each proton is removed step-wise and the pH is calculated for each step.
Calculations of Weak Acids and Bases
Переглядів 1383 місяці тому
In this video we calculate the pH of solutions of weak acids and weak bases. We also calculate the Ka of a weak acid from the pH and then using percent dissociation.
Understanding the pH and pOH Scales
Переглядів 583 місяці тому
In this video we discuss the properties of the pH and pOH scales. Specifically how they are negative logarithmic scales and how concentration changes as you move units along the scale.
FDA approval of TRYVIO - aprocitentan
Переглядів 5943 місяці тому
directory of Chem Help ASAP videos: www.chemhelpasap.com/youtube/ channel email: chemhelpasap1@gmail.com This video describes the approval of TRYVIO, which contains aprocitentan as its active pharmaceutical ingredient. TRYVIO is approved to treat hypertension in patients taking other antihypertensive drugs. TRYVIO was approved by the U.S. FDA on March 19, 2024. The sponsor of the NDA was Idorsi...
discovery of nivasorexant, an orexin-1 receptor antagonist
Переглядів 3873 місяці тому
directory of Chem Help ASAP videos: www.chemhelpasap.com/youtube/ link to J. Med. Chem. article: pubs.acs.org/doi/10.1021/acs.jmedchem.3c01894 channel email: chemhelpasap1@gmail.com This video describes the discovery of nivasorexant, a selective orexin-1 receptor antagonists for the treatment of obsessive compulsive disorders. The content of this video was reported by scientists of Idorsia Phar...
FDA approval of REZDIFFRA (resmetirom) for NASH/MASH treatment
Переглядів 1,2 тис.4 місяці тому
FDA approval of REZDIFFRA (resmetirom) for NASH/MASH treatment
Defining Acids and Bases with Arrhenius and Bronsted Lowry
Переглядів 514 місяці тому
Defining Acids and Bases with Arrhenius and Bronsted Lowry
FDA approval of EXBLIFEB - cefepime & enmetazobactam
Переглядів 3614 місяці тому
FDA approval of EXBLIFEB - cefepime & enmetazobactam
lead selection & lead optimization - playlist welcome
Переглядів 1504 місяці тому
lead selection & lead optimization - playlist welcome
preclinical drug safety programs - playlist welcome
Переглядів 704 місяці тому
preclinical drug safety programs - playlist welcome
discovery of NX-2127, a BTK degrader for B-cell malignancies
Переглядів 3474 місяці тому
discovery of NX-2127, a BTK degrader for B-cell malignancies
Using ICE Tables to Calculate Equilibrium Concentrations
Переглядів 604 місяці тому
Using ICE Tables to Calculate Equilibrium Concentrations
Heterogeneous Equilibrium Expressions
Переглядів 324 місяці тому
Heterogeneous Equilibrium Expressions
how can you have bromine on a wedge but have it in the plane on the newman projection
I might be a little to comment by late i mean frecking after 3 years cool video
Can i get this paper, please
I liked how you said it’s a tough topic at the end…yes it is lol
Great video really helped
Wonderful!! Best of luck to you in your studies.
Is resmetirom for NAFLD or for NASH or for both?
Resmetirom is approved for NASH, not NAFLD. It might help on NAFLD, but the drug's efficacy was measured on steatohepatitis.
U help a lottt! Thank you so much❤❤❤ currently binge watching your videos!!❤️❤️
Wonderful! I hope they help.
Very good video! I am currently looking for online small molecule databases for molecular docking screening and machine training. I noticed that you also have a lot of research papers based on molecular structure screening and then docking with specific proteins, but I didn't find the specific database name and access from the papers. Could you please show me some details on how to find these database resources for free (or for a fee) from the internet. Thanks~~
I am definitely not an expert on docking, but I do know that the most commonly used free molecular database is zinc (zinc.docking.org/). The Zinc database is specifically curated for searching and downloading in a form that can be readily imported into docking software. For full disclosure, I have never imported compounds from the Zinc database. When I have done modeling and docking, I have mostly modified ligands that are already bound in a protein (i.e., modified a PDB cocrystal structure).
I love the video
Thank you for watching, and I'm glad the video was helpful for you.
His voice reminds me of georgie from young sheldon 😂❤
poor georgie!
Great explanation thanks ❤
Chemists are dumb. Ethyl=eth-uhl, hexyl=hex-uhl, sulfonyl=sulf-on-uhl, alkyl=alk-uhl, carbonyl=carbon-eel.. what?!
Can we do this as a one pot reaction like starting from benzyl chloride + azide + acetylene + catalyst?
I am sure that somebody has tried to generate the alkyl azide in situ, but I haven't seen it. I am a bit wary of forming different metal-azide salts, which doesn't happen if you pre-form the alkyl azide.
great lectures. thanks
Kongen
Bare hyggelig
At 5.05 time stamp, why negative charge came near lone pair???
That negative charge is the formal charge on the carbon atom - the carbon atom that bears the lone pair. Keep in mind that the carbon also has a C-H bond (not shown), so the carbon has three bonds (one to the carbon chain, one to oxygen, one to hydrogen) and a lone pair. That gives it a formal charge of -1.
Clear amazing 🎉
informative
Thank you very much, in my opinion that was one of the best explanations of this topic on net if not the best one!!
Please could you provide a sample of your results table
Thank you for saving this med student last minute 🙏
I was confused why my reaction mixture is showing 2 spots extra at 1 hr in TLC I got the answer.......thank you so much
I have understood this in the space of 12 I attended lectures all term without understanding a thing
I am so glad you found it helpful! Kinetics is a tough topic!
thank you! this helped a lot!!
Thanks. Really helped a lot. Great choice of problems.
You're a lifesaver and I cannot believe there aren't more views and likes. You're extremely appreciated by me!!
I am glad you found it helpful!
You're a life saver thank you
You are very welcome! Take care.
what if the parentheses is first?
thank you very much for this video.. If I want to modify one design molecule is there any parameter (add or change group in the chemical formula) that can raise the hERG to be more than 10 (less toxic)?
Thank you buddy 🎉
Why the tertiary Alkyl halides undergoes the SN2 reaction in the presence of NaBH4 Please can you me out to understand that
Very concice and clear. Also quit a professional look to the video. Bravo! Tango - foxtrot even!
Is it use in alcohal hepatitis
thanks
Perfect! Every time I recrystallize NBS, I get nervous about the generated bromine during the heating process, but I guess it is all a part of it.
Hi! Is there a difference between shape and geometry? Do we need to consider the lone pairs while determining the shape?
I consider shape and geometry to be interchangeable (but follow the lead of your instructor). Bond angle, however, is different. The lone pair does influence the geometry, but lone pairs are specifically included in the geometry. NH3 is trigonal pyramidal. "Trigonal" captures the hydrogens. "Pyramidal" gets the hydrogens and the peak of the nitrogen. The lone pairs, however, are not specifically called out by the geometry. The lone pairs do affect the geometry.
Very helpful video. I'm glad I found it
Thank you and welcome to the channel.
Thank you for brief and useful information. I will be watching for remembiring sometimes.
Glad it was helpful!
You're incredible! Your videos are fantastic! I wish every teacher could be as pedagogically skilled as you are.
Thank you for your support. I'm glad you find the videos helpful.
I am a Chemistry PhD student who is currently taking an NMR Spectroscopy course. I have to say, you did a great job at explaining the problem in simple terms. Good job!
Thank you so much for the feedback. (I hope your PhD courses and research are going well.)
Please the link of the paper that ur procdure from...or just tell me the ratio of the alkyne , azide, cu(pph3)No3 , toulen.. u used
If the oxidative cleavage is O3/Zn-H2O, would that be reductive or oxidative work up?
Hello sir can you please suggest me a polymer NMR reference book I was given a task to find H1 and C13 NMR of polyvinyl chloride, polystyrene but I am unable to find it on browser
Thank you very much
Hi I wanna more info please 😊
Sure! Email me at Karin@ChemHelpASAP.com and I can give you more details about the prep courses I am currently running!
Would be interesting to know its solubility and permeability
If my R group on the electrophile contains Alpha Hydrogens, can I do a standard Aldol RXN and then dehydration even though it won't work for condensation?
Generally, yes, but you can still run into problems. The late 1970s and early 1980s were full of research trying to fix this problem, which is essentially making sure that the ketone enolate that is formed initially does only what you want it to do. The real problem is that the ketone enolate is not just a nucleophile but also a base. As a base, it can deprotonate other alpha-protons in the reaction, including an alpha proton on the electrophile (if present). The stoichiometry of the base (LDA) is also very important. The reaction can be quite complex, and my treatment in these videos is just an introduction.
Clear and concise video, thank you
Thank you it’s clear and helps a lot!
Great. Thanks for watching.
Is there any possibility that you can introduce some prodrug design and synthesis work?